JNJ 17203212

SIGMA/J3580 - ≥98% (HPLC)

Synonym: N¹-(3-Trifluoromethylpyrid-2-yl)-N⁴-(4-trifluoromethylpyrid-2-yl)carbamoylpiperazine

CAS Number: 821768-06-3
Empirical Formula (Hill Notation): C₁₇H₁₅F₆N₅O
Molecular Weight: 419.32
Linear Formula: C₁₇H₁₅F₆N₅O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-J3580-5MG	5 mg	DISCONTINUED
45-J3580-25MG	25 mg	DISCONTINUED

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to off-white
form	powder
InChI	1S/C17H15F6N5O/c18-16(19,20)11-3-4-13(25-10-11)26-15(29)28-8-6-27(7-9-28)14-12(17(21,22)23)2-1-5-24-14/h1-5,10H,6-9H2,(H,25,26,29)
InChI key	JFRYYGVYCWYIDQ-UHFFFAOYSA-N
originator	Johnson & Johnson
SMILES string	FC(F)(F)c1c(nccc1)N2CCN(CC2)C(=O)Nc3ncc(cc3)C(F)(F)F
solubility	DMSO: >20 mg/mL
storage temp.	−20°C

Biochem/physiol Actions:	JNJ 17203212 is a reversible, competitive and potent TRPV1 antagonist that does not inhibit related TRP channels such as TRPV2, TRPV4, or TRPA1. Listed in BJP with IC50= 65 nM. TRPV1 channels are activated by heat, capsaicin and the endocannabinoid anandamide. Interest in TRPV1 antagonists in the transmission and modulation of pain.
Biochem/physiol Actions:	JNJ 17203212 is a reversible, competitive and potent TRPV1 antagonist.
Features and Benefits:	This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS06
Signal word	Danger
Hazard statements	H301-H319
Precautionary statements	P301 + P310-P305 + P351 + P338
Hazard Codes	Xn,Xi
Risk Statements	22-36
Safety Statements	26
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.