Ketoprofen
SIGMA/K1751 - ≥98% (TLC)
Synonym: 2-
CAS Number: 22071-15-4
Empirical Formula (Hill Notation): C16H14O3
Molecular Weight: 254.28
EC Number: 244-759-8
MDL Number: MFCD00055790
Linear Formula: C16H14O3
Product Type: Chemical
| assay | ≥98% (TLC) |
| biological source | synthetic |
| form | powder |
| InChI | 1S/C16H14O3/c1-11(16(18)1 |
| InChI key | DKYWVDODHFEZIM-UHFFFAOYSA |
| originator | Bayer |
| Quality Level | 200  |
| SMILES string | CC(C(O)=O)c1cccc(c1)C(=O) |
| solubility | ethanol: 50 mg/mL, clear, colorless to yellow |
| Application: | Ketoprofen has been used: • as sample to analyse the effects of long storage period by chromatographic and microscopic techniques • as a nonselective COX inhibitor to inject subcutaneously in rats to study its effect on stress/methamphetamine hydrochloride-induced changes in occludin, claudin-5 and COX-2 protein immunoreactivity, truncation of β-dystroglycan, brain water content and fluorescein isothiocyanate-dextran extravasation • in phosphate buffer to study its ability to inhibit heat-induced denaturation of albumin |
| Biochem/physiol Actions: | It serves as an efficient drug to treat ankylosing spondylitis, rheumatoid arthritis and osteoarthritis. It also has antipyretic and analgesic effects. Ketoprofen prevents the action of prostaglandin synthetase. |
| Biochem/physiol Actions: | Non-steroidal anti-inflammatory compound that is selective for COX-1. |
| Features and Benefits: | This compound was developed by Bayer . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Ketoprofen belongs to the class of 2-arylpropionic acid. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264 - P270 - P301 + P310 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 2 |
| Purity | ≥98% (TLC) |
| UNSPSC | 12352200 |