KB-R7943
SIGMA/K4144 - ≥98% (HPLC), powder
Synonym: 2-
CAS Number: 182004-64-4 (free base)
Empirical Formula (Hill Notation): C16H17N3O3S·CH3SO3H
Molecular Weight: 427.50
MDL Number: MFCD00952138
Linear Formula: C16H17N3O3S·CH3SO3H
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | off-white to tan |
| form | powder |
| InChI | 1S/C16H17N3O3S.CH4O3S/c17 |
| InChI key | WGIKEBHIKKWJLG-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | CS(O)(=O)=O.NC(=N)SCCc1cc |
| solubility | DMSO: >10 mg/mL |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. |
| Biochem/physiol Actions: | KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard Codes | N |
| Risk Statements | 50 |
| Safety Statements | 61 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |

