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KB-R7943

SIGMA/K4144 - ≥98% (HPLC), powder

Synonym: 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester, methanesulfonate (1:1); Carbamimidothioic acid

CAS Number: 182004-64-4 (free base)
Empirical Formula (Hill Notation): C16H17N3O3S·CH3SO3H
Molecular Weight: 427.50
MDL Number: MFCD00952138
Linear Formula: C16H17N3O3S·CH3SO3H
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-K4144-5MG 5 mg
$162.00
1/EA
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45-K4144-25MG 25 mg
$513.00
1/EA
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assay ≥98% (HPLC)
color off-white to tan
form powder
InChI 1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
InChI key WGIKEBHIKKWJLG-UHFFFAOYSA-N
Quality Level 100 
SMILES string CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1
solubility DMSO: >10 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX.
Biochem/physiol Actions: KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane.
Packaging: 5, 25 mg in glass bottle
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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