KR-32568

SIGMA/K4389 - ≥98% (HPLC), solid

Synonym: [5-(2-Methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine

CAS Number: 852146-73-7
Empirical Formula (Hill Notation): C₁₃H₁₂FN₃O₂
Molecular Weight: 261.25
MDL Number: MFCD08705324
Linear Formula: C₁₃H₁₂FN₃O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-K4389-5MG	5 mg	$261.00 1/EA		Add To Favorites
45-K4389-25MG	25 mg	$949.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white
form	solid
InChI	1S/C13H12FN3O2/c1-7-2-3-8(14)6-9(7)10-4-5-11(19-10)12(18)17-13(15)16/h2-6H,1H3,(H4,15,16,17,18)
InChI key	DTLDHYBZLVASJQ-UHFFFAOYSA-N
Quality Level	100
SMILES string	Cc1ccc(F)cc1-c2ccc(o2)C(=O)NC(N)=N
solubility	DMSO: ~10 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	Sodium/hydrogen exchanger-1 (NHE-1) inhibitor.
Biochem/physiol Actions:	Sodium/hydrogen exchanger-1 (NHE-1) inhibitor; IC₅₀= 0.23 μM; inhibited NHE-1-mediated rabbit platelet swelling; in anesthetized rats, reduced infarct size from 67% (control) to 43% (at 0.1 mg/kg) and 24% (at 1.0 mg/kg); reduced number of ventricular premature beats from 530 to 266 (at 0.1 mg/kg) and 115 (at 1.0 mg/kg); reduced ventricular fibrillation incidence from 17 to 8 (0.1 mg/kg) and 0 (1.0 mg/kg); implications for research and treatment of myocardial ischemic diseases.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315 - H319 - H335
Precautionary statements	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.