L-Kynurenine

SIGMA/K8625 - ≥98% (HPLC)

Synonym: β-Anthraniloyl-L-alanine; L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS Number: 2922-83-0
Empirical Formula (Hill Notation): C₁₀H₁₂N₂O₃
Molecular Weight: 208.21
MDL Number: MFCD00069912
Linear Formula: C₁₀H₁₂N₂O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-K8625-25MG	25 mg	$82.90 1/EA		Add To Favorites
45-K8625-100MG	100 mg	$110.00 1/EA		Add To Favorites
45-K8625-500MG	500 mg	$348.00 1/EA		Add To Favorites
45-K8625-1G	1 g	$589.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	detection
assay	≥98% (HPLC)
form	powder
InChI	1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1
InChI key	YGPSJZOEDVAXAB-QMMMGPOBSA-N
mp	219 °C
Quality Level	200
SMILES string	N[C@@H](CC(=O)c1ccccc1N)C(O)=O

Application:	L-Kynurenine has been used as a standard for indoleamine-2,3-dioxygenase (IDO) assay. It has also been used as a standard to extract and quantify kynurenine from cultured cells and media.
Biochem/physiol Actions:	Key intermediate in the breakdown pathway of tryptophan.
Biochem/physiol Actions:	L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. It is involved in a variety of neurological processes and diseases. L-Kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
mp	219 °C
UNSPSC	12352209

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