DCA Deblock
SIGMA/L023050 - configured for (ÄKTA® and OligoPilot®)
Product Type: Chemical
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| color | clear |
| compatibility | configured for (ÄKTA® and OligoPilot®) |
| concentration | 42.2-51.6 g/L (DCA content, titration) |
| description | with Toluene |
| impurities | ≤200 ppm water content (Karl Fischer) |
| Quality Level | 200  |
| storage condition | dry at room temperature |
| type | for DNA synthesis |
| Application: | DCA Deblock solution facilitates removal of the DMT that allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction. |
| General description: | Deblock solution containing dichloroacetic acid (DCA) in toluene removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. This solution contains toluene / Dichloroactic Acid (97/3 v/v). |
| Legal Information: | ÄKTA is a registered trademark of Cytiva |
| Legal Information: | OligoPilot is a registered trademark of Cytiva |
| Preparation Note: | Toluene / Dichloroacetic acid 97/3 (v/v) |
| Symbol |      GHS02,GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H225 - H304 - H315 - H318 - H336 - H351 - H360FD - H373 - H410 |
| Precautionary statements | P210 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P331 |
| Hazard Codes | F,Xn,N |
| Risk Statements | 63-11-36/38-48/20-50-65-67 |
| Safety Statements | 16-26-36/37-61-62 |
| RIDADR | UN2924 - class 3 - PG 2 - EHS - acidic - Flammable liquids, corr |
| WGK Germany | WGK 2 |
| Flash Point(F) | 39.2 °F |
| Flash Point(C) | 4.0 °C |
| UNSPSC | 41116004 |