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L-α-Lysophosphatidylcholine from Glycine max (soybean)

SIGMA/L0906 - ≥99%, lyophilized powder

Synonym: 1-Acyl-sn-glycero-3-phosphocholine; L-α-Lysolecithin

CAS Number: 9008-30-4
EC Number: 232-715-0
MDL Number: MFCD00131444
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-L0906-25MG 25 mg
 $88.80
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45-L0906-100MG 100 mg
 $311.00
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45-L0906-500MG 500 mg
 $1070.00
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assay ≥99%
biological source soybean
description zwitterionic
form lyophilized powder
functional group phospholipid
lipid type phosphoglycerides
Quality Level 200 
shipped in ambient
storage temp. −20°C
Biochem/physiol Actions: Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Biochem/physiol Actions: Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
Packaging: Packaged under Argon.
Preparation Note: Prepared by the action of phospholipase A on soybean L-α-phosphatidylcholine (P 6263).
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99%
Storage Temp. −20°C
UNSPSC 51321705

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