L-α-Lysophosphatidylcholine from Glycine max (soybean)
SIGMA/L0906 - ≥99%, lyophilized powder
Synonym: 1-Acyl-sn-
CAS Number: 9008-30-4
EC Number: 232-715-0
MDL Number: MFCD00131444
Product Type: Chemical
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| assay | ≥99% |
| biological source | soybean |
| description | zwitterionic |
| form | lyophilized powder |
| functional group | phospholipid |
| lipid type | phosphoglycerides |
| Quality Level | 200  |
| shipped in | ambient |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. |
| Biochem/physiol Actions: | Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels. |
| Packaging: | Packaged under Argon. |
| Preparation Note: | Prepared by the action of phospholipase A on soybean |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| Storage Temp. | −20°C |
| UNSPSC | 51321705 |