Lactoferricin B, fragment 4-14 trifluoroacetate salt
SIGMA/L1290 - ≥95% (HPLC)
Synonym: bLFC (26-36); bovine lactoferricin
Empirical Formula (Hill Notation): C70H113N25O13S
Molecular Weight: 1544.87
MDL Number: MFCD04040902
Linear Formula: C70H113N25O13S
Product Type: Chemical
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| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| assay | ≥95% (HPLC) |
| mode of action | cell membrane | interferes |
| Quality Level | 200  |
| solubility | H2O: soluble |
| storage temp. | −20°C |
| Amino Acid Sequence: | Arg-Arg-Trp-Gln-Trp-Arg-M |
| Application: | Lactoferricin B, fragment 4-14 trifluoroacetate salt has been used to study effect of lactoferricin on cell proliferation of human colon cancer cells. It has been used in study of ultraviolet light-mediated DNA damage in human colon cancer cells. |
| Biochem/physiol Actions: | Antibiotic peptide in colostrum and milk that protects from bacterial infection at mucosal surfaces. |
| Biochem/physiol Actions: | Lactoferricin B also suppresses liver and lung metastasis in murine melanomas and lymphomas. In addition, it causes cell death in human leukemic and carcinoma cell lines. It is effective against Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Proteus vulgaris, Yersinia enterocolitica, Pseudomonas aeruginosa, Campylobacter jejuni, Staphylococcus aureus, Streptococcus mutans, Corynebacterium diphtheriae, Listeria monocytogenes and Clostridium perfringens. |
| General description: | Chemical structure: peptide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |