Lactoperoxidase from bovine milk
SIGMA/L2005 - lyophilized powder (essentially salt-free), ≥200 units/mg protein
Synonym: Donor:hydrogen peroxide oxidoreductase; Peroxidase
CAS Number: 9003-99-0
EC Number: 232-668-6
MDL Number: MFCD00131484
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L2005-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L2005-25MG
| absorbance ratio | A412/280 nm 0.7-0.9 |
| biological source | bovine milk |
| form | lyophilized powder (essentially salt-free) |
| InChI | 1S/H2O3/c1-3-2/h1-2H |
| InChI key | JSPLKZUTYZBBKA-UHFFFAOYSA |
| Quality Level | 200  |
| 400 |
|
| SMILES string | [O+H2]O[O-] |
| specific activity | ≥200 units/mg protein |
| storage temp. | −20°C |
| UniProt accession no. | P80025  |
| Analysis Note: | Protein determined by Lowry method. |
| Application: | Lactoperoxidase from bovine milk has been used as a standard for milk lactoperoxidase to study the role of H2O2 in the inhibition of Staphylococcus aureus growth by Lactococcus garvieae in the presence of lactoperoxidase in raw milk. It has also been used in lactoperoxidase-mediated iodination to prepare radiolabeled peptides. |
| Biochem/physiol Actions: | Lactoperoxidase catalyzes the oxidation of iodide to iodine by hydrogen peroxide. This activity provides a gentle, specific alternative to chloramine T for the radioiodination of proteins and DNA. |
| Biochem/physiol Actions: | Lactoperoxidase contributes to the antimicrobial system of milk by inactivating a wide range of micro-organisms. This lactoperoxidase-mediated antimicrobial system is also identified in human secretions such as tear-fluid, saliva, and milk. Lactoperoxidase catalyzes the oxidation of molecules by releasing H2O2. The product exhibits antimicrobial activity. |
| General description: | Lactoperoxidase is a major enzyme present in bovine milk and belongs to the peroxidase family. It is present in both plants and animals. The enzyme structure comprises a single polypeptide chain made up of 612 amino acid residues. |
| Other Notes: | One unit will oxidize 1.0 μmole of 2,2′-azino-bis(3-ethylben |
| Packaging: | 1, 5 mg in glass bottle |
| Packaging: | 10, 25 mg in poly bottle |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317 - H334 |
| Precautionary statements | P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| activity | specific activity: ≥200 units/mg protein |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 1.11.1.7 ( BRENDA | IUBMB ) |
| UNSPSC | 12352204 |