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Lincomycin hydrochloride

SIGMA/L2774 - BioReagent, suitable for cell culture

Synonym: Lincocin hydrochloride; Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride

CAS Number: 859-18-7
Empirical Formula (Hill Notation): C18H34N2O6S · HCl
Molecular Weight: 443.00
EC Number: 212-726-7
MDL Number: MFCD00083647
Linear Formula: C18H34N2O6S · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-L2774-1MU 1000000 units
 $81.60
1/EA		 Add To Favorites
45-L2774-5MU 5000000 units
 $284.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L2774-1MU
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L2774-5MU

 

antibiotic activity spectrum Gram-positive bacteria
color white to yellow-white
InChI 1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1
InChI key POUMFISTNHIPTI-BOMBIWCESA-N
mode of action protein synthesis | interferes
potency 800-900 units per mg
product line BioReagent
Quality Level 200 
SMILES string Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
solubility H2O: 4 mL, clear, colorless to faintly yellow (200 mg + 4 mL H2O)
storage temp. 2-8°C
technique(s) cell culture | mammalian: suitable
Application: Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It is produced by Streptomyces lincolnensis var. lincolnensis, and has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.
Biochem/physiol Actions: Mode of action: Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA.†

Antimicrobial spectrum: Lincomycin hydrochloride is effective against gram-positive bacteria.
General description: Chemical structure: macrolide
Packaging: 1000000, 5000000 units in glass bottle
Preparation Note: This product is soluble in water at 50 mg/mL, yielding a clear, colorless solution.
Storage Temp. 2-8°C
UNSPSC 12352207

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