α-Lactose monohydrate

SIGMA/L3625 - ≥99% total lactose basis (GC)

Synonym: β-D-Gal-(1→4)-α-D-Glc; 4-O-β-D-Galactopyranosyl-α-D-glucose; Milk sugar

CAS Number: 5989-81-1
Empirical Formula (Hill Notation): C₁₂H₂₂O₁₁ · H₂O
Molecular Weight: 360.31
MDL Number: MFCD00150747
Linear Formula: C₁₂H₂₂O₁₁ · H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-L3625-1KG	1 kg	$66.60 1/EA	Add To Favorites
45-L3625-5KG	5 kg	$209.00 1/EA	Add To Favorites

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This image depicts SKU: L3625-1KG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99% total lactose basis (GC)
biological source	bovine milk
color	white to off-white
form	powder
impurities	≤0.05% Glucose
	≤4% β-lactose
InChI	1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
InChI key	WSVLPVUVIUVCRA-KPKNDVKVSA-N
mp	219 °C ((426 °F ))
Quality Level	200
SMILES string	[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
solubility	water: 100 mg/mL, clear, colorless
storage temp.	room temp

Application:	Crystal size, a key character of lactose crystallization affecting microstructure, surface chemistry and reconstitution of milk powder.: This study uses alpha-lactose monohydrate as a standard to investigate how crystal size affects the physical properties of milk powder, which is crucial for optimizing production processes in the dairy industry (Qi X et al., 2024 ). Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with alpha-Lactose Monohydrate.: Explores the critical role of alpha-lactose monohydrate, as an excipient together with terbutaline sulfate in optimizing particle interactions for enhanced performance of inhalable therapeutics (Ma CY et al., 2023 ). Terahertz time-domain spectroscopy for the investigation of tablets prepared from roller compacted granules.: This research utilizes alpha-lactose monohydrate to examine the properties of pharmaceutical tablets, offering insights into material characteristics that affect drug delivery systems (Anuschek M et al., 2023 ).
Biochem/physiol Actions:	alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.
Biochem/physiol Actions:	Lactose is a dissacharide formed by the condensation of one galactose and one glucose molecule. Lactose is the major sugar in the milk of most species, typically present between 2-8%.
Other Notes:	To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Packaging:	1 kg in poly bottle
Packaging:	5 kg in poly drum

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% total lactose basis (GC)
mp	219 °C ((426 °F ))
Storage Temp.	room temp
UNSPSC	12352201

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