L-α-Lysophosphatidylcholine from egg yolk

SIGMA/L4129 - ≥99%, Type I, powder

Synonym: 1-Acyl-sn-glycero-3-phosphocholine; L-α-Lysolecithin

CAS Number: 9008-30-4
EC Number: 232-715-0
MDL Number: MFCD00131444
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-L4129-25MG	25 mg	$72.00 1/EA	Add To Favorites
45-L4129-100MG	100 mg	$211.00 1/EA	Add To Favorites
45-L4129-500MG	500 mg	$636.00 1/EA	Add To Favorites
45-L4129-1G	1 g	$1150.00 1/EA	Add To Favorites

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This image depicts SKU: L4129-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99%
biological source	egg yolk
color	white
description	zwitterionic
form	powder
functional group	phospholipid
lipid type	phosphoglycerides
Quality Level	200
shipped in	ambient
storage temp.	−20°C
type	Type I

Analysis Note:	Contains primarily palmitic and stearic acids.
Application:	L-α-Lysophosphatidylcholine from egg yolk has been used: • as a surfactant • as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis • as a demyelinating agent for nerve • as a component in sperm nuclei preparation buffer
Biochem/physiol Actions:	Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Biochem/physiol Actions:	Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na⁺ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K⁺ channels.
Packaging:	1 g in poly bottle
Packaging:	25, 100, 500 mg in poly bottle
Preparation Note:	Prepared by the action of phospholipase A on egg L-α-phosphatidylcholine.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
Storage Temp.	−20°C
UNSPSC	12352211

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