Luteinizing hormone releasing hormone human acetate salt

SIGMA/L7134 - ≥98% (HPLC), powder

Synonym: Gonadoliberin; Gonadotropin releasing hormone; LH-RH

CAS Number: 71447-49-9
Empirical Formula (Hill Notation): C₅₅H₇₅N₁₇O₁₃
Molecular Weight: 1182.29
MDL Number: MFCD00133489
Linear Formula: C₅₅H₇₅N₁₇O₁₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-L7134-5MG	5 mg	$161.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
form	powder
InChI	1S/C55H75N17O13.2C2H4O2/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36;21-2(3)4/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60);21H3,(H,3,4)/t36-,37-,38-,39-,40-,41-,42-,43-;;/m0../s1
InChI key	QOVPLTBEZAJSHY-VIRDRFNDSA-N
mol wt	M_r 1182.33
Quality Level	200
SMILES string	CC(O)=O.CC(O)=O.CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4c[nH]cn4)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N6CCC[C@H]6C(=O)NCC(N)=O
storage temp.	−20°C
UniProt accession no.	P01148

Amino Acid Sequence:	Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Application:	Luteinizing hormone releasing hormone human acetate salt has been used: • for synchronization of the ovulations • for pre-absorption of the anti-GnRH antibody in staining procedures • to study pituitary sensitivity to GnRH in presence of endocrine disrupting compound
Biochem/physiol Actions:	Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
Biochem/physiol Actions:	Stimulates release of gonadotrophins from anterior pituitary.
Other Notes:	free peptide
Other Notes:	Lyophilized from 0.5% acetic acid
Other Notes:	pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Symbol	GHS08
Signal word	Danger
Hazard statements	H360
Precautionary statements	P201 - P308 + P313
Hazard Codes	T
Risk Statements	60
Safety Statements	53-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	51111800

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