Linoleic acid sodium salt

SIGMA/L8134 - ≥97% (GC)

Synonym: Sodium linolate; Sodium linoleate; cis-9,cis-12-Octadecadienoic acid sodium salt

CAS Number: 822-17-3
Empirical Formula (Hill Notation): C₁₈H₃₁NaO₂
Molecular Weight: 302.43
EC Number: 212-491-0
MDL Number: MFCD00063202
Linear Formula: C₁₈H₃₁O₂Na
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-L8134-100MG	100 mg	$59.80 1/EA	Add To Favorites
45-L8134-500MG	500 mg	$94.30 1/EA	Add To Favorites
45-L8134-1G	1 g	$148.00 1/EA	Add To Favorites
45-L8134-5G	5 g	$518.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	general analytical life science and biopharma
assay	≥97% (GC)
biological source	plant oil (safflower)
color	white
form	powder
functional group	carboxylic acid
InChI	1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
InChI key	WYPBVHPKMJYUEO-NBTZWHCOSA-M
lipid type	omega FAs
mp	230 °C (446 °F)
Quality Level	300
shipped in	ambient
SMILES string	[Na+].CCCCCC=C/CC=C/CCCCCCCC([O-])=O
solubility	methanol: 50 mg/mL, clear, yellow
storage temp.	−20°C
technique(s)	activity assay: suitable

Application:	Linoleic acid sodium salt has been used: • in the β-carotene-linoleic acid assay • as a component in basal medium to treat peripheral blood mononuclear cells (PBMCs) • in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 HEPES (4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid) to incubate human trophoblast-derived choriocarcinoma cells (BeWo) and study its effects on adherens junctions (AJ) marker level, cell layer permeability, and intracellular lipid accumulation
Biochem/physiol Actions:	Linoleic acid, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin. The deficiency of linoleic acid may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants. It is used in cosmetic and personal care products. Linoleic acid is mainly used as emollients or moisturizers for skin, nails, and hair.
Features and Benefits:	• High-quality molecule suitable for mulitple research applications • Commonly employed in Metabolomics and Biochemical studies
General description:	Linoleic acid, an essential omega-6 polyunsaturated fatty acid (PUFA), serves as a precursor to arachidonic acid (AA), necessary for synthesizing prostaglandins and other eicosanoids. Being an essential fatty acid, linoleic acid must be acquired through diet as the body cannot produce it. Deficiencies in linoleic acid are linked to health issues such as impaired wound healing, growth retardation, and dermatitis. Arachidonate 15 Lipoxygenase (15-LO) metabolizes linoleic acid in both plants and animals, forming 9- and 13-hydroxyoctadecadienoic acid (HODE). This versatile molecule finds applications in biochemical, metabolomics, and lipidomics research, enabling investigations into various metabolic pathways and providing insights into lipid functions in living organisms.
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1, 5 g in serum bottle
Packaging:	100, 500 mg in serum bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315
Hazard Codes	Xi
Risk Statements	38
Safety Statements	36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (GC)
mp	230 °C (446 °F)
Storage Temp.	−20°C
UNSPSC	12352211

To Order From a Quote