α-Lactose monohydrate

SIGMA/L8783 - ≥99% total lactose basis (GC), BioXtra

Synonym: β-D-Gal-(1→4)-α-D-Glc; 4-O-β-D-Galactopyranosyl-α-D-glucose; Milk sugar

CAS Number: 5989-81-1
Empirical Formula (Hill Notation): C₁₂H₂₂O₁₁ · H₂O
Molecular Weight: 360.31
MDL Number: MFCD00150747
Linear Formula: C₁₂H₂₂O₁₁ · H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-L8783-10MG	10 mg	$31.30 1/EA	Add To Favorites
45-L8783-1KG	1 kg	$140.00 1/EA	Add To Favorites
45-L8783-5KG	5 kg	$551.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

anion traces	chloride (Cl^-): ≤0.05%
	sulfate (SO₄^2-): ≤0.05%
assay	≥99% total lactose basis (GC)
biological source	bovine milk
cation traces	Al: ≤0.0005%
	Ca: ≤0.005%
	Cu: ≤0.0005%
	Fe: ≤0.0005%
	K: ≤0.02%
	Mg: ≤0.0005%
	Na: ≤0.005%
	NH₄⁺: ≤0.05%
	Pb: ≤0.001%
	Zn: ≤0.0005%
color	white to off-white
form	powder
ign. residue	≤0.1%
impurities	≤0.01% Phosphorus (P)
	≤0.1% Insoluble matter
InChI	1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
InChI key	WSVLPVUVIUVCRA-KPKNDVKVSA-N
mp	219 °C ((426 °F ))
product line	BioXtra
Quality Level	200
SMILES string	[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
solubility	H₂O: 1 M, clear, colorless

Application:	Insights into the potential of rheological measurements in development of dry powder inhalation formulations.: This article investigates rheological properties and their implications in the development of inhalation formulas where a-Lactose monohydrate plays a crucial role (Almansour et al., 2022 ). Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance.: The study provides a comparative analysis of spray-congealing and wet-sieving processes in engineering carrier particles for inhalation, utilizing a-Lactose monohydrate (Pinto et al., 2021 ). Conversion of a-lactose monohydrate to anhydrous form with superior tabletability by twin-screw extrusion at elevated temperature.: Discusses a method for converting a-Lactose monohydrate to a more compressible anhydrous form, enhancing its application in tablet manufacturing (Batra et al., 2020 ).
Biochem/physiol Actions:	alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.
Other Notes:	To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Packaging:	1 kg in poly bottle
Packaging:	10 mg in glass bottle
Packaging:	5 kg in poly drum

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% total lactose basis (GC)
mp	219 °C ((426 °F ))
UNSPSC	12352201

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