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Loratadine

SIGMA/L9664 - ≥98% (HPLC), powder

Synonym: 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester; Loratidine

CAS Number: 79794-75-5
Empirical Formula (Hill Notation): C22H23N2O2Cl
Molecular Weight: 382.88
MDL Number: MFCD00672869
Linear Formula: C22H23N2O2Cl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-L9664-10MG 10 mg
 $222.00
1/EA		 Add To Favorites
45-L9664-50MG 50 mg
 $753.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L9664-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L9664-50MG

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
InChI key JCCNYMKQOSZNPW-UHFFFAOYSA-N
originator Schering Plough
Quality Level 200 
SMILES string CCOC(=O)N1CCC(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24
solubility DMSO: soluble 50 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Biochem/physiol Actions: Loratadine is a non-sedating histamine H1-receptor antagonist. Shown to inhibit the two-pore domain potassium channel K2P18.1 (also called TRESK or KCNK18).
Biochem/physiol Actions: Non-sedating histamine H1-receptor antagonist.
Features and Benefits: This compound was developed by Schering Plough . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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