(−)-Tetramisole hydrochloride
SIGMA/L9756 - ≥99% (GC)
Synonym: (S)-(−)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride; L(−)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride; Levamisole hydrochloride
CAS Number: 16595-80-5
Empirical Formula (Hill Notation): C11H12N2S · HCl
Molecular Weight: 240.75
EC Number: 240-654-6
MDL Number: MFCD00012675
Linear Formula: C11H12N2S · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L9756-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: L9756-10G
| antibiotic activity spectrum | parasites |
| assay | ≥99% (GC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C11H12N2S.ClH/c1-2-4-9 |
| InChI key | LAZPBGZRMVRFKY-HNCPQSOCSA |
| mode of action | enzyme | inhibits |
| mp | 228-230 °C |
| Quality Level | 200  |
| SMILES string | Cl.C1CN2C[C@@H](N=C2S1)c3 |
| solubility | water: 50 mg/mL, clear, colorless to faintly yellow |
| Application: | Suitable for inhibition of various mammalian alkaline phosphatase (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited. Not for veterinary use. |
| Biochem/physiol Actions: | Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors. Very effective in treatment of ascariasis (hookworm infestation). Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages. |
| Other Notes: | Levamisole hydrochloride is soluble in water at 50mg/mL yielding a clear, colorless solution. Solutions are stable at 2-8°C for ~1 month. |
| Packaging: | 5, 10 g in poly bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 + P330 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (GC) |
| mp | 228-230 °C |
| UNSPSC | 12352202 |