LOPAC®1280
SIGMA/LO1280
Synonym: Library of Pharmacologically Active Compounds
Product Type: Chemical
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| drug control | Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet |
| form | liquid |
| Quality Level | 100  |
| shipped in | dry ice |
| storage temp. | −20°C |
| Application: | LOPAC®1280 has been used: • in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model • to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction • in screening of small molecules for activating bone morphogenetic protein (BMP) signaling • in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein |
| Features and Benefits: | Collection of 1,280 Pharmacologically-Active Sigma Compounds |
| Features and Benefits: | Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience: • Apoptosis • G Proteins & Cyclic Nucleotides • Gene Regulation & Expression • Ion Channels • Lipid Signaling • Multi-Drug Resistance • Neurotransmission • Phosphorylation |
| Features and Benefits: | SDFile provided to construct a database containing: • Structure • Primary Name • Secondary Name • Pharmacological Activity • Product Number • Rack Position |
| Features and Benefits: | To request a list of components, please visit sigma.com/LOPAC |
| General description: | Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO). |
| Legal Information: | LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300 . |
| Symbol |     GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H300 + H310 + H330 - H315 - H317 - H318 - H334 - H340 - H350 - H360FD - H362 - H371 - H373 - H410 |
| Precautionary statements | P263 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 188.6 °F - closed cup |
| Flash Point(C) | 87 °C - closed cup |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |