(±)-Methadone hydrochloride
SIGMA/M0267 - powder, ≥98%
Synonym: 6-
CAS Number: 1095-90-5
Empirical Formula (Hill Notation): C21H27NO · HCl
Molecular Weight: 345.91
EC Number: 214-140-7
MDL Number: MFCD00058014
Linear Formula: C21H27NO · HCl
Product Type: Chemical
| assay | ≥98% |
| color | white to off-white |
| drug control | kontrollierte Droge in Deutschland |
| USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal) | |
| form | powder |
| InChI | 1S/C21H27NO.ClH/c1-5-20(2 |
| InChI key | FJQXCDYVZAHXNS-UHFFFAOYSA |
| originator | Novartis |
| Quality Level | 200 ![]() |
| SMILES string | Cl.CCC(=O)C(CC(C)N(C)C)(c |
| solubility | H2O: 50 mg/mL, clear, colorless to yellow |
| Biochem/physiol Actions: | μ opioid receptor agonist that desensitizes both the μ opioid receptor and the δ opioid receptor on chronic exposure; narcotic analgesic, characterized by a gradual onset of action and prolonged, milder withdrawal; may also block L-type calcium channels independently of its effects on opioid receptors. |
| Features and Benefits: | This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Legal Information: | German Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG. English This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies. |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H300 - H336 |
| Precautionary statements | P301 + P310 + P330 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| UNSPSC | 12352200 |


