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Sulfur 42

SIGMA/M076000

Synonym: Phenyl-3H-1,2,4-dithiazol-3-one

CAS Number: 7047-10-1
Empirical Formula (Hill Notation): C8H5NOS2
Molecular Weight: 195.26
MDL Number: MFCD02311276
Linear Formula: C8H5NOS2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-M076000-1G 1 g
$216.00
1/EA
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45-M076000-2G 2 g
$246.00
1/EA
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assay ≥99.0% (reversed phase HPLC)
color faintly yellow to yellow
form solid
impurities ≤0.1% water content (Karl Fischer)
InChI 1S/C8H5NOS2/c10-8-9-7(11-12-8)6-4-2-1-3-5-6/h1-5H
InChI key LKDWQHQNDDNHSC-UHFFFAOYSA-N
packaging 2 g of 2 g M076000-2G
  pkg of 1 g M076000-1G
product line Proligo Reagents
Quality Level 200 
SMILES string O=C1SSC(C2=CC=CC=C2)=N1
solubility acetonitrile: 0.1 M, clear
storage temp. 2-8°C
suitability conforms to structure for H-NMR
type for DNA synthesis
Application: Sulfur 42 is suitable for use instead of an Oxidizer during the synthesis cycle to manufacture thioated oligonucleotides.
Features and Benefits: • Sulfur 42 is at least 4 times more reactive than Beaucage reagent or PADS
• Crystalline powder
• Odourless, no foul smell
• Solubility in ACN up to 0.28M at (+10 °C); no need to applied a co-solvent like in DCM, THF
• The solvent for the dissolution of the reagent should be dry (< 50 ppm) in order to minimize P=O impurities
•  Stable in ACN solution for at least 21 days
•  Recommended reaction time for the sulfurization in oligonucleotide synthesis for a 0.1M solution is 60 sec
General description: Sulfur 42 is a sulfurization reagent.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.0% (reversed phase HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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