Sulfur 42
SIGMA/M076000
Synonym: Phenyl-3H-
CAS Number: 7047-10-1
Empirical Formula (Hill Notation): C8H5NOS2
Molecular Weight: 195.26
MDL Number: MFCD02311276
Linear Formula: C8H5NOS2
Product Type: Chemical
| assay | ≥99.0% (reversed phase HPLC) |
| color | faintly yellow to yellow |
| form | solid |
| impurities | ≤0.1% water content (Karl Fischer) |
| InChI | 1S/C8H5NOS2/c10-8-9-7(11- |
| InChI key | LKDWQHQNDDNHSC-UHFFFAOYSA |
| packaging | 2 g of 2 g M076000-2G |
| pkg of 1 g M076000-1G | |
| product line | Proligo Reagents |
| Quality Level | 200 ![]() |
| SMILES string | O=C1SSC(C2=CC=CC=C2)=N1 |
| solubility | acetonitrile: 0.1 M, clear |
| storage temp. | 2-8°C |
| suitability | conforms to structure for H-NMR |
| type | for DNA synthesis |
| Application: | Sulfur 42 is suitable for use instead of an Oxidizer during the synthesis cycle to manufacture thioated oligonucleotides. |
| Features and Benefits: | • Sulfur 42 is at least 4 times more reactive than Beaucage reagent or PADS • Crystalline powder • Odourless, no foul smell • Solubility in ACN up to 0.28M at (+10 °C); no need to applied a co-solvent like in DCM, THF • The solvent for the dissolution of the reagent should be dry (< 50 ppm) in order to minimize P=O impurities • Stable in ACN solution for at least 21 days • Recommended reaction time for the sulfurization in oligonucleotide synthesis for a 0.1M solution is 60 sec |
| General description: | Sulfur 42 is a sulfurization reagent. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (reversed phase HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |

