Ethyl methanesulfonate
SIGMA/M0880 - liquid
Synonym: Ethyl mesylate; Methanesulfonic acid ethyl ester
CAS Number: 62-50-0
Empirical Formula (Hill Notation): C3H8O3S
Molecular Weight: 124.16
EC Number: 200-536-7
MDL Number: MFCD00007559
Linear Formula: CH3SO3CH2CH3
Product Type: Chemical
| bp | 85-86 °C/10 mmHg (lit.) |
| density | 1.206 g/mL at 20 °C |
| form | liquid |
| InChI | 1S/C3H8O3S/c1-3-6-7(2,4)5 |
| InChI key | PLUBXMRUUVWRLT-UHFFFAOYSA |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | CCOS(C)(=O)=O |
| Application: | Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts, yeast human embryonic kidney cell lines and human lymphocytes. |
| Biochem/physiol Actions: | Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana. |
| Packaging: | 1, 5, 10, 25, 100 g in glass bottle |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H340 - H350 - H361f |
| Precautionary statements | P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 46-22-40 |
| Safety Statements | 53-36/37-45 |
| RIDADR | UN 3082 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 212.0 °F |
| Flash Point(C) | 100 °C |
| bp | 85-86 °C/10 mmHg (lit.) |
| Density | 1.206 g/mL at 20 °C |
| Refractive Index | n |
| UNSPSC | 12352108 |