Dihydrocapsaicin

SIGMA/M1022 - from Capsicum sp., ≥85%

Synonym: 6,7-Dihydrocapsaicin; 8-Methyl-N-vanillylnonanamide; N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonenamide

CAS Number: 19408-84-5
Empirical Formula (Hill Notation): C₁₈H₂₉NO₃
Molecular Weight: 307.43
MDL Number: MFCD00057794
Linear Formula: C₁₈H₂₉NO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M1022-50MG	50 mg	$167.00 1/EA	Add To Favorites
45-M1022-250MG	250 mg	$486.00 1/EA	Add To Favorites
45-M1022-1G	1 g	$1470.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M1022-1G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥85%
biological source	Capsicum sp.
InChI	1S/C18H29NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h10-12,14,20H,4-9,13H2,1-3H3,(H,19,21)
InChI key	XJQPQKLURWNAAH-UHFFFAOYSA-N
Quality Level	200
SMILES string	COc1cc(CNC(=O)CCCCCCC(C)C)ccc1O
storage temp.	2-8°C

Application:	Dihydrocapsaicin has been used: • as a standard to analyze the level of dihydrocapsaicin in endogenous An2 and capsaicin synthase silenced fruits • as an external standard to determine the variability in capsaicinoid content in different landraces of capsicum • in the activation or ablation of capsaicin-sensitive primary afferents (CSPA) fibres
Biochem/physiol Actions:	Dihydrocapsaicin/8-methyl-N-vanillylnonanamide; N-[−4-hydroxy-3-methoxybenzyl] 8-methylnonanamide (DHC) is an active component of capsaicinoids in chili peppers. DHC is capable of reducing body temperature. Hence it is considered as a pharmaceutical-induced hypothermia (PIH) candidate to treat cardiac arrest (CA) patients. It may possess anti-cancer, anti-inflammation, antioxidant, anti-obesity properties. DHC might help in the reduction of oxidative stress and inflammation in ischemia and reperfusion (I/R) injury. DHC can repress nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway.
Biochem/physiol Actions:	VR1 vanilloid receptor agonist.
Other Notes:	Capsaicin analog.
Packaging:	1 g in glass bottle
Packaging:	250 mg in glass bottle
Packaging:	50 mg in poly bottle

Symbol	GHS06
Signal word	Danger
Hazard statements	H300 - H315 - H319 - H335
Precautionary statements	P261 - P264 - P280 - P280 - P301 + P310 + P330 - P304 + P340 + P312
Hazard Codes	T
Risk Statements	25-36/37/38
Safety Statements	26-45
RIDADR	UN 3462 6.1 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥85%
Storage Temp.	2-8°C
UNSPSC	12352200

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