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Naproxen sodium

SIGMA/M1275 - 98.0-102.0%

Synonym: (S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid sodium salt

CAS Number: 26159-34-2
Empirical Formula (Hill Notation): C14H13NaO3
Molecular Weight: 252.24
EC Number: 247-486-2
MDL Number: MFCD00058507
Linear Formula: C14H13NaO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M1275-5G 5 g
 $102.00
1/EA		 Add To Favorites
45-M1275-25G 25 g
 $297.00
1/EA		 Add To Favorites
45-M1275-50G 50 g
 $509.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M1275-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M1275-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M1275-25G

 

assay 98.0-102.0%
biological source synthetic (organic)
form powder
InChI 1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
InChI key CDBRNDSHEYLDJV-FVGYRXGTSA-M
originator Bayer
Quality Level 200 
SMILES string [Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O
solubility water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
Application: Naproxen sodium has been used to evaluate the thermodynamics of biomolecular interaction with bovine and human serum albumin. It has also been used to evaluate its efficiency in reducing the response of spinal dorsal horn neurons to noxious knee joint rotation.
Biochem/physiol Actions: Cyclooxygenase (Prostaglandin H synthase 1 and 2) inhibitor.
Biochem/physiol Actions: Naproxen binds preferably to serum albumin. The S-enantiomer of naproxen is 28-fold more potential as an anti-inflammatory drug compared to the R-isomer. The R-isomer is found to be a liver toxin and causes gastrointestinal disorders.
Features and Benefits: This compound was developed by Bayer . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Naproxen belongs to phenylacetic acid class of Non-steroidal anti-inflammatory drugs (NSAIDs).
Packaging: 5, 25, 50 g in poly bottle
Purity 98.0-102.0%
UNSPSC 12352200

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