3,3′-Methylene-bis(4-hydroxycoumarin)
SIGMA/M1390
Synonym: Bishydroxycoumarin; Dicoumarol; Dicumarol
CAS Number: 66-76-2
Empirical Formula (Hill Notation): C19H12O6
Molecular Weight: 336.29
EC Number: 200-632-9
MDL Number: MFCD00006857
Linear Formula: C19H12O6
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: M1390-5G
This image depicts SKU: M1390-5G
| assay | ≥98% (TLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C19H12O6/c20-16-10-5-1 |
| InChI key | DOBMPNYZJYQDGZ-UHFFFAOYSA |
| mp | 290-292 °C (lit.) |
| Quality Level | 100  |
| SMILES string | OC1=C(CC2=C(O)c3ccccc3OC2 |
| solubility | pyridine: 50 mg/mL, clear, faintly yellow to brownish-yellow |
| Biochem/physiol Actions: | Prototype of the 4-hydroxycoumarin class of anticoagulants, which act as vitamin K antagonists, preventing formation of prothrombin. There are many reports that dicumarol also inhibits NADPH:quinone oxidoreductase (NQO(1)). In one, it inhibited NQO(1) in a pancreatic cancer cell line, causing increased formation of superoxide and inhibiting cell growth. |
| Packaging: | 5, 25 g in poly bottle |
| Symbol |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 - H372 - H411 |
| Precautionary statements | P260 - P264 - P270 - P273 - P301 + P310 - P314 |
| Hazard Codes | T,N |
| Risk Statements | 22-48/25-51/53 |
| Safety Statements | 37-45-61 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | 290-292 °C (lit.) |
| UNSPSC | 12352103 |