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Menadione sodium bisulfite

SIGMA/M2518 - BioReagent, suitable for cell culture, ≥95% (TLC)

Synonym: 2-Methyl-1,4-naphthoquinone sodium bisulfite

CAS Number: 130-37-0
Empirical Formula (Hill Notation): C11H9NaO5S
Molecular Weight: 276.24
EC Number: 204-987-0
MDL Number: MFCD00051456
Linear Formula: C11H9NaO5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M2518-100G 100 g
 $93.90
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M2518-100G

 

assay ≥95% (TLC)
biological source synthetic (organic)
color white to off-white
form powder
InChI 1S/C11H10O5S.Na/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;/h2-5H,6H2,1H3,(H,14,15,16);/q;+1/p-1
InChI key XDPFHGWVCTXHDX-UHFFFAOYSA-M
mol wt Mw 276.24 g/mol
product line BioReagent
Quality Level 200 
SMILES string [Na+].CC1(CC(=O)c2ccccc2C1=O)S([O-])(=O)=O
solubility water: soluble 50 mg/mL, clear, colorless to light yellow
storage temp. −20°C
technique(s) cell culture | mammalian: suitable
  cell culture | plant: suitable
Application: Menadione sodium bisulfite has been used:
• as a free radical inducer to study its effects on oxidative stress in sunflower seedlings
• as a positive control to produce mitochondrial O2 during the measurement of O2 in human proximal tubular cell lines
• as a redox-cycling mitochondrial pro-oxidant to study its effects on protein kinase B (AKT) and mechanistic target of rapamycin (mTOR) signaling in cardiac cells
Biochem/physiol Actions: Menadione sodium bisulfite (MSB) is a derivative of vitamin K3 and has been studied in the treatment of hemorrhagic diseases like hypoprothrombinemia and neonatal hemorrhage, caused due to vitamin K3 deficiency. It is also considered a nutritional supplement for animals. MSB shows anticancer effects. It also protects plants from biotic and abiotic stress.
Disclaimer: The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
Other Notes: Water soluble vitamin K3.
Packaging: 100 g in poly bottle
Purity ≥95% (TLC)
Storage Temp. −20°C
UNSPSC 12352205

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