Marimastat

SIGMA/M2699 - ≥98% (HPLC)

Synonym: BB2516, (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl] propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide

CAS Number: 154039-60-8
Empirical Formula (Hill Notation): C₁₅H₂₉N₃O₅
Molecular Weight: 331.41
MDL Number: MFCD00866242
Linear Formula: C₁₅H₂₉N₃O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M2699-5MG	5 mg	$243.00 1/EA	Add To Favorites
45-M2699-25MG	25 mg	$1070.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
form	solid
InChI	1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
InChI key	OCSMOTCMPXTDND-OUAUKWLOSA-N
Quality Level	100
shipped in	wet ice
SMILES string	CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C
solubility	DMSO: ≥20 mg/mL
storage temp.	−20°C

Application:	Marimastat has been used as an inhibitor of: • metalloproteinase 2/9 (MMP2/9), to study its effects on exercise-mediated interleukin-6 (IL-6) release in mice • metalloproteinase, to determine protease activity in Pseudomonas aeruginosa cultures • metalloproteinase 10 (MMP10), to study its effect on monoclonal antibody H3 binding to MMP10
Biochem/physiol Actions:	Marimastat is a broad spectrum matrix metalloprotease (MMP) inhibitor
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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