Synonym: CPC-200; MDL-72527DA; N,N′-Bis(2,3-butadienyl)-1,4-butanediamine dihydrochloride; N1,N4-Bis(2,3-butadienyl)-1,4-butanediamine hydrochloride
CAS Number: 93565-01-6
Empirical Formula (Hill Notation): C12 H20 N2·2 HCl
Molecular Weight: 265.22
MDL Number: MFCD13152261
Linear Formula: C12 H20 N2·2 HCl
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to brown |
| form |
powder |
| InChI |
1S/C12H20N2.2ClH/c1-3-5-9-13-11-7-8-12-14-10-6-4-2;;/h5-6,13-14H,1-2,7-12H2;2*1H |
| InChI key |
ITVRWVVFVHINOH-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
Cl.Cl.C=C=CCNCCCCNCC=C=C |
| solubility |
H2O: 15 mg/mL, clear |
| storage temp. |
room temp |
| Biochem/physiol Actions: |
MDL 72527is an inhibitor of polyamine oxidase (spermine oxidase SMO). |
| Biochem/physiol Actions: |
MDL 72527is an inhibitor of polyamine oxidase (spermine oxidase SMO). It blocks the production of H2O2 and increases the cells survival. Polyamine catabolism is one of the major causes of the ROS production of prostate cells in general and androgen-induced enhancement of ROS in androgen-dependent CaP cells in particular. Reports suggest that androgen stimulation of prostate cancer results in accumulation of ROS, which lead to progression of cancer, such progression is control by MDL 72527. |
| Packaging: |
5, 25 mg in glass bottle |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
GHS07