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N-Methyl-D-aspartic acid

SIGMA/M3262 - ≥98% (TLC), solid

Synonym: (R)-2-(Methylamino)succinic acid; NMDA

CAS Number: 6384-92-5
Empirical Formula (Hill Notation): C5H9NO4
Molecular Weight: 147.13
MDL Number: MFCD00004226
Linear Formula: C5H9NO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M3262-25MG 25 mg
 $70.80
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45-M3262-100MG 100 mg
 $178.00
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45-M3262-250MG 250 mg
 $365.00
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45-M3262-1G 1 g
 $1120.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M3262-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M3262-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M3262-250MG

 

application(s) cell analysis
assay ≥98% (TLC)
color white
form solid
InChI 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1
InChI key HOKKHZGPKSLGJE-GSVOUGTGSA-N
mp 189-190 °C
Quality Level 200 
SMILES string CN[C@H](CC(O)=O)C(O)=O
technique(s) cell culture | mammalian: suitable
Application: N-Methyl-D-aspartic acid has been used to induce N-methyl-d-aspartic acid (NMDA) toxicity, cultures of retinal cells were supplemented with NMDA.
Biochem/physiol Actions: Excitotoxic amino acid. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy.
Biochem/physiol Actions: N-Methyl-D-aspartic acid (NMDA) plays a crucial role in release of luteinizing hormone and PRL (prolactin) in the pituitary gland and GnRH (gonadotropin releasing hormone) in the hypothalamus. It acts as a specific agonist for NMDA type glutamate receptors.
General description: N-Methyl-D-aspartic acid (NMDA) is an endogenously generated molecule in rat nervous system and endocrine glands. NMDA is present at low level (nmol/g) in the adenohypophysis, hypothalamus, brain, and testis. NMDA is derived from D-Asp by an S-adenosylmethionine-dependent enzyme also referred to as NMDA synthase.
Packaging: 1, 5 g in poly bottle
Packaging: 25, 100, 250 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp 189-190 °C
UNSPSC 12352209

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