α-Mangostin
SIGMA/M3824 - ≥98% (HPLC)
Synonym: α-MG; alpha-Mangostin
CAS Number: 6147-11-1
Empirical Formula (Hill Notation): C24H26O6
Molecular Weight: 410.46
EC Number: 448-420-7
MDL Number: MFCD00135200
Linear Formula: C24H26O6
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: M3824-100MG
This image depicts SKU: M3824-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: M3824-50MG
This image depicts SKU: M3824-50MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M3824-10MG
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C24H26O6/c1-12(2)6-8-1 |
| InChI key | GNRIZKKCNOBBMO-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | COc1c(O)cc2Oc3cc(O)c(CC= |
| solubility | methanol: 1 mg/mL, clear, very light yellow |
| storage temp. | 2-8°C |
| Application: | α-Mangostin has been used: • to study its protective effect against oxidative stress mediated-retinal cell death • to study its role as an antigenotoxic agent in DNA protection against oxidative damage • to understand its anti-bacterial activity against Staphylococcus epidermidis RP62A |
| Biochem/physiol Actions: | Xanthone derivative isolated from mangosteen (Garcinia mangostana). Antioxidant and anti-inflammatory. |
| Biochem/physiol Actions: | Xanthone derivative isolated from mangosteen (Garcinia mangostana). Antioxidant and anti-inflammatory. α-mangostin has been shown to induce apoptosis via the mitochondrial pathway, reduce cell proliferation and inhibit tumorigenesis. |
| Biochem/physiol Actions: | α-Mangostin displays various pharmacological properties both in in vitro and in vivo studies. These include antimicrobial, anticarcinogenic, antidiabetic, neuroprotective, hepatoprotective and anti-inflammatory properties. |
| General description: | α-Mangostin (α-MG) is the most abundant phytochemical derived from the pericarp of Garcinia mangostana L.. It is a tetraoxygenated diprenylated xanthone. The chemical structure of α-MG molecule is 1,3,6-trihydroxy-7-methox |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 50, 100 mg in poly bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352212 |