Mucin from bovine submaxillary glands
SIGMA/M3895 - Type I-S
Synonym: MUC
CAS Number: 84195-52-8
EC Number: 282-357-4
MDL Number: MFCD00131629
Product Type: Chemical
Mucins are a diverse family of densely glycosylated proteins. Mucin domains within the protein core are rich in threonine, serine and hydroxyproline enabling post-translational O-glycosylation.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M3895-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M3895-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M3895-500MG
| biological source | bovine submaxillary glands |
| composition | Bound sialic acids, 9-24% |
| form | powder |
| Quality Level | 200  |
| storage temp. | −20°C |
| technique(s) | electrophoresis: suitable |
| type | Type I-S |
| UniProt accession no. | P98091  |
| Application: | Mucin from bovine submaxillary glands has been used: • in the quantification of mucin • as a component of artificial tear solution • as a substrate for recombinant sialidase Gardnerella vaginalis • to investigate a galactose-specific lectin from the red marine alga Ptilota filicina • to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa) |
| Biochem/physiol Actions: | Albuminoid substance in mucus which gives it its ropy consistency |
| Biochem/physiol Actions: | Bovine submaxillary mucin (BSM) is thermally stable up to 85°C. The terminal domain regions are key for the adsorption functionality of mucin. |
| General description: | Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes. It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain. The sialic acid contributes to 30% of the molecular weight of mucin. The central domain has many tandem repeats. |
| General description: | Neuraminidase substrate. |
| Other Notes: | Similar to M 4503, but produced by Sigma. |
| Packaging: | 1 g in poly bottle |
| Packaging: | 100, 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |