6-Methylmercaptopurine riboside
SIGMA/M4002 - ≥99% (HPLC)
Synonym: 6MMPr; 6-(Methylthio)-9-β-D-ribofuranosyl-9H-purine
CAS Number: 342-69-8
Empirical Formula (Hill Notation): C11H14N4O4S
Molecular Weight: 298.32
EC Number: 206-442-2
Linear Formula: C11H14N4O4S
Product Type: Chemical
| assay | ≥99% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C11H14N4O4S/c1-20-10-6 |
| InChI key | ZDRFDHHANOYUTE-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | O[C@H]([C@@H](CO)O1)[C@@H |
| solubility | methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | 6-Methylmercaptopurine riboside (6MMPR) has been used as a phosphoribosyl pyrophosphate amidotransferase inhibitor to study its effects on DNA replication in a retinoblastoma (Rb) phosphorylation-independe |
| Application: | 6-Methylmercaptopurine riboside (6MMPr) is used in studies on thiopurine metabolism by enzymes such as inosine-5′-monophosphate dehydrogenase and thiopurine methyltransferase. 6MMPr may also be used to study mechanisms of bovine viral diarrhea virus (BVDV) inhibition. |
| Biochem/physiol Actions: | 6-Methylmercaptopurine riboside (6MMPR) is a modified thiopurine nucleoside involved in the inhibition of purine synthesis. It exhibits anti-viral effects against various viruses. 6MMPR is an analog of purine and an inhibitor of nerve growth factor-activated protein kinase N. |
| Packaging: | 1 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |

