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Mometasone furoate

SIGMA/M4074 - ≥98% (HPLC)

Synonym: (11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

CAS Number: 83919-23-7
Empirical Formula (Hill Notation): C27H30Cl2O6
Molecular Weight: 521.43
MDL Number: MFCD00866003
Linear Formula: C27H30Cl2O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M4074-5MG 5 mg
 $91.20
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45-M4074-25MG 25 mg
 $351.00
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts M4074-5MG.

 

assay ≥98% (HPLC)
color white to off-white
form powder
InChI 1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
InChI key WOFMFGQZHJDGCX-ZULDAHANSA-N
optical activity [α]/D +50 to +60°, c = 0.5 in methanol
originator Schering Plough
Quality Level 100 
SMILES string C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl
solubility DMSO: ≥20 mg/mL
storage temp. 2-8°C
Application: Mometasone furoate has been used to study its effect on Leishmania major amastigotes.
Biochem/physiol Actions: Mometasone furoate is a 17-heterocyclic intranasal corticosteroid. It is effectively used as a first-line daily intranasal therapeutic for allergic rhinitis and nasal polyposis. Mometasone furoate is also used as an adjunct to anti-bacterials for treating acute rhinosinusitis. In addition, it relieves the symptoms of asthma in both adults and adolescents by exhibiting a broad spectrum of anti-inflammatory properties.
Biochem/physiol Actions: Mometasone furoate is an anti-inflammatory glucocorticoid.
Features and Benefits: This compound is featured on the Nuclear Receptors (Steroids)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Schering Plough . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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