Myelin Oligodendrocyte Glycoprotein (44-54), Rat, Mouse
SIGMA/M4324 - lyophilized powder
Synonym: MOG (44-54)
Empirical Formula (Hill Notation): C61H94N20O15
Molecular Weight: 1347.52
Linear Formula: C61H94N20O15
Product Type: Chemical
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| color | white |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | deionized water: soluble |
| storage temp. | −20°C |
| UniProt accession no. | Q61885  |
| Q63345 |
| Amino Acid Sequence: | Phe-Ser-Arg-Val-Val-His-L |
| Biochem/physiol Actions: | The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation. |
| Other Notes: | Lyophilized from 0.1% TFA in H2O |
| Physical form: | Lyophilized from 0.1% aqueous TFA. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |