(±)-Mevalonolactone
SIGMA/M4667 - ~97% (titration)
Synonym: (±)-β-Hydroxy-β-methyl-δ-valerolactone; (±)
CAS Number: 674-26-0
Empirical Formula (Hill Notation): C6H10O3
Molecular Weight: 130.14
EC Number: 211-615-0
MDL Number: MFCD00006648
Linear Formula: C6H10O3
Product Type: Chemical
| assay | ~97% (titration) |
| InChI | 1S/C6H10O3/c1-6(8)2-3-9-5 |
| InChI key | JYVXNLLUYHCIIH-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | CC1(O)CCOC(=O)C1 |
| storage temp. | −20°C |
| Application: | (±)-Mevalonolactone is used to: • study the effect of statin on the prenylation of Ras and Rho GTPases • analyse the isoprenoid biosynthesis pathways in Listeria monocytogenes • study the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells) |
| General description: | Alkaline hydrolysis of mevalonolactone gives mevalonate. Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation. |
| Other Notes: | May also be liquid! |
| Packaging: | 1, 5, 10 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 235.4 °F - closed cup |
| Flash Point(C) | 113 °C - closed cup |
| Purity | ~97% (titration) |
| Storage Temp. | −20°C |
| UNSPSC | 12352108 |