Monensin sodium salt

SIGMA/M5273 - 90-95% (TLC)

Synonym: Monensin A sodium salt

CAS Number: 22373-78-0
Empirical Formula (Hill Notation): C₃₆H₆₁NaO₁₁
Molecular Weight: 692.85
EC Number: 244-941-7
MDL Number: MFCD00077826
Linear Formula: C₃₆H₆₁NaO₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M5273-500MG	500 mg	$85.70 1/EA	Add To Favorites
45-M5273-1G	1 g	$156.00 1/EA	Add To Favorites
45-M5273-5G	5 g	$512.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5273-1G

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	fungi
	Gram-negative bacteria
	Gram-positive bacteria
	parasites
	viruses
assay	90-95% (TLC)
InChI	1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40;/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40);/q;+1/p-1/t19-,20-,21+,22+,23-,24-,25-,26+,27+,28-,29+,30-,31+,33-,34-,35?,36-;/m0./s1
InChI key	XOIQMTLWECTKJL-BEMBKCOJSA-M
mode of action	cell membrane \| interferes
Quality Level	200
SMILES string	[H][C@]1([C@@]2(CC)O[C@]([C@@]3(C)OC4(C[C@H](O)[C@@H](C)[C@@]([H])([C@@H](C)[C@@H](OC)[C@@H](C([O-])=O)C)O4)CC3)([H])CC2)[C@@H](C)C[C@]([H])([C@@]5([H])O[C@@](O)(CO)[C@H](C)C[C@@H]5C)O1.[Na+]
storage temp.	2-8°C

Application:	Monensin sodium salt has been used: • for the intracellular staining of cytokines • to study its effects on the regulation of nuclear factor-κ B (NF-κB ) activation • as a positive control to study its effects on in vitro rumen fermentation
Biochem/physiol Actions:	Na⁺ ionophore; blocks glycoprotein secretion; may induce catecholamine secretion from chromaffin cells. Useful in potentiometric and spectroscopic studies of alkali metal ion complexes.
General description:	Chemical structure: polyether
General description:	Monensin is a polyether ionophoric antibiotic, which is produced by Streptomyces cinnamonensis. It is used to treat bacterial, fungal and parasitic infections. Monensin prevents the growth of colon cancer cells. It facilitates the transport of sodium and potassium ions between intracellular and extracellular spaces. Monensin prevents coccidiosis in poultry production.
Packaging:	1, 5 g in poly bottle
Packaging:	500 mg in poly bottle
Preparation Note:	Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

Symbol	GHS06,GHS08,GHS09
Signal word	Danger
Hazard statements	H300 - H319 - H334 - H373 - H411
Precautionary statements	P260 - P264 - P273 - P301 + P310 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	T
Risk Statements	25
Safety Statements	36/37/39-45
RIDADR	UN 3462 6.1 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	90-95% (TLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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