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Miltefosine

SIGMA/M5571 - ≥98% (perchloric acid titration)

Synonym: Choline hexadecyl phosphate; HePC; Hexadecyl phosphocholine

CAS Number: 58066-85-6
Empirical Formula (Hill Notation): C21H46NO4P
Molecular Weight: 407.57
MDL Number: MFCD00133396
Linear Formula: C21H46NO4P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M5571-50MG 50 mg
 $124.00
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45-M5571-100MG 100 mg
 $233.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5571-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5571-50MG

 

assay ≥98% (perchloric acid titration)
biological source synthetic (organic)
description zwitterionic
form powder
functional group phospholipid
InChI 1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
InChI key PQLXHQMOHUQAKB-UHFFFAOYSA-N
lipid type phospholipids
Quality Level 200 
SMILES string [O-]P(OCC[N+](C)(C)C)(OCCCCCCCCCCCCCCCC)=O
solubility H2O: 10 mg/mL, clear, colorless
storage temp. room temp
Application:

  • Easy one-pot synthesis of multifunctionalized indole-pyrrole hybrids as a new class of antileishmanial agents.: This study underlines the necessity for innovative treatments amidst growing resistance to established drugs such as miltefosine which is used as a positive control reference, potentially setting a new direction for antileishmanial drug development (Ciccone et al., 2024 ).
Biochem/physiol Actions: Inhibitor of protein kinase C and of phosphatidylcholine synthesis. Used for the treatment of visceral and cutaneous leishmaniasis. Active against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis
Packaging: 50, 100 mg in glass bottle
Purity ≥98% (perchloric acid titration)
Storage Temp. room temp
UNSPSC 51191904

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