Menadione sodium bisulfite
SIGMA/M5750 - ≥95% (TLC)
Synonym: 2-
CAS Number: 130-37-0
Empirical Formula (Hill Notation): C11H9NaO5S
Molecular Weight: 276.24
EC Number: 204-987-0
MDL Number: MFCD00051456
Linear Formula: C11H9NaO5S
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5750-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5750-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M5750-1KG
| application(s) | cell analysis |
| assay | ≥95% (TLC) |
| biological source | synthetic |
| color | white to off-white |
| form | powder |
| InChI | 1S/C11H10O5S.Na/c1-11(17( |
| InChI key | XDPFHGWVCTXHDX-UHFFFAOYSA |
| originator | Eli Lilly |
| Quality Level | 200  |
| SMILES string | [Na+].CC1(CC(=O)c2ccccc2C |
| solubility | H2O: ≥50 mg/mL, clear, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | Menadione sodium bisulfite has been used: • as a priming agent in tomato for improving salt tolerance • to induce reactive oxygen species (ROS) in human lung epithelium BEAS-2B microtissues • to induce endogenous superoxide production in mouse C17.2 neural stem cells |
| Biochem/physiol Actions: | Menadione sodium bisulfite is a water-soluble form of menadione, which belongs to the Vitamin K class of compounds. These are necessary for the biosynthesis of prothrombin and other blood clotting factors. Menadione is a prothrombogenic compound and is used as a model quinone in cell culture and in vivo investigations. Menadione has been shown to affect gap-junctional intercellular communication by mediation of tyrosine phosphorylation. Menadione has demonstrated cytotoxic activity against a variety of cell lines and can induce apoptosis in cultured cells, such as osteoclasts and osteoblasts, via elevation of peroxide and superoxide radical levels. An HPLC method for detection of menadione sodium bisulfite in multivitamin formulations has been published. A chemiluminescence assay for menadione sodium bisulfite in pharmaceutical preparations and biological fluids has been reported. |
| Features and Benefits: | This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Other Notes: | Water soluble vitamin K3. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 25, 100 g in poly bottle |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H410 |
| Precautionary statements | P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 |
| Hazard Codes | Xi,N |
| Risk Statements | 36/38-50/53 |
| Safety Statements | 24/25-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (TLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |