M344

SIGMA/M5820 - ≥98% (HPLC), powder

Synonym: 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide; MS 344, D237; N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide

CAS Number: 251456-60-7
Empirical Formula (Hill Notation): C₁₆H₂₅N₃O₃
Molecular Weight: 307.39
MDL Number: MFCD03453554
Linear Formula: C₁₆H₂₅N₃O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M5820-1MG	1 mg	$252.00 1/EA	Add To Favorites
45-M5820-5MG	5 mg	$728.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20)
InChI key	MXWDSZWTBOCWBK-UHFFFAOYSA-N
Quality Level	100
SMILES string	CN(C)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
solubility	DMSO: 10 mg/mL, clear
storage condition	protect from light
storage temp.	2-8°C

Biochem/physiol Actions:	M344 is a HDAC inhibitor and subtype selective for HDAC6 over HDAC1.
Biochem/physiol Actions:	M344 is a HDAC inhibitor; subtype selective for HDAC6 over HDAC1. M344 inhibits HDAC (IC₅₀ = 100 nM) and also inhibits hyperacetylation of histone H4, terminal cell differentiation, transcription (γ-globin), and tumor cell death.
Features and Benefits:	This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging:	1, 5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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