MART-1 (27-35), Human
SIGMA/M6324
Synonym: Antigen LB39-AA (27-35) (human); Antigen SK29-AA (27-35) (human); Melan-A Protein (27-35) (human); Melanoma Antigen Recognized By T-Cells 1 (27-35) (human)
Product Type: Chemical
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| color | white |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | water, double-distilled: soluble |
| storage temp. | −20°C |
| Amino Acid Sequence: | Ala-Ala-Gly-Ile-Gly-Ile-L |
| Biochem/physiol Actions: | Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma. |
| General description: | Melanoma-associated antigen recognized by T cells-1 (MART-1), also known as Melan-A, is encoded by the gene mapped to human chromosome 9p24.1. The encoded protein is a hydrophobic transmembrane protein. MART-1 is mainly expressed in skin and retinae melanocytes. |
| General description: | The peptide represents amino acids 27-35 of MART-1 protein that is the melanoma antigen recognized by T cells. This peptide mimics the natural epitope that is presented by T cells in humans with reactivity to melanoma cells. |
| Other Notes: | Lyophilized from 0.1% TFA in H2O |
| Physical form: | Lyophilized from 0.1% aqueous TFA |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |