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N-(2-Mercaptopropionyl)glycine

SIGMA/M6635

Synonym: Tiopronin

CAS Number: 1953-02-2
Empirical Formula (Hill Notation): C5H9NO3S
Molecular Weight: 163.19
EC Number: 217-778-4
MDL Number: MFCD00004861
Linear Formula: CH3CH(SH)CONHCH2COOH
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M6635-5G 5 g
 $0.00
1/EA
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45-M6635-10G 10 g
 $0.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M6635-5G

 

application(s) cell analysis
peptide synthesis
assay ≥98% (TLC)
color white
form powder
InChI 1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8)
InChI key YTGJWQPHMWSCST-UHFFFAOYSA-N
mp 98-100 °C
Quality Level 100 
SMILES string CC(S)C(=O)NCC(O)=O
Application: N-(2-Mercaptopropionyl)glycine or Tiopronin has been used:
• in the preparation of polyethylenimine (PEI)-coated gold microparticles (PEI-gold) for biolistic delivery of nucleic acids
• to study the role of reactive oxygen species (ROS) at the reperfusion stage in in vivo isoflurane preconditioning-induced neuroprotection
• as a ROS inhibitor to study its effect on lysophosphatidylcholine (LPC)-induced inflammasome activation
Biochem/physiol Actions: N-(2-Mercaptopropionyl)glycine (NMPG) is a thiol compound associated with autoimmune hypoglycemia. It is a diffusible antioxidant and reduces the severity of colonic injury. NMPG also relieves myeloperoxidase activity and stimulates hypoxia-inducible factor-1 (HIF-1) - vascular endothelial growth factor (VEGF) pathway for ulcer healing.
Biochem/physiol Actions: N-(2-Mercaptopropionyl)glycine is a free radical scavenger.
Packaging: 5, 10, 50, 100 g in poly bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P264 - P270 - P301 + P312 - P501
Hazard Codes Xn
Risk Statements 22
Safety Statements 36/37
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp 98-100 °C
UNSPSC 12352209

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