Anti-Matrix Metalloproteinase-24, Hinge Region antibody produced in rabbit
SIGMA/M6684 - ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution
Synonym: Anti-MMP-24; Anti-MT5-MMP
MDL Number: MFCD03097031
Product Type: Chemical
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| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous glycerol solution |
| mol wt | antigen 65 kDa |
| Quality Level | 200  |
| shipped in | wet ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: suitable |
| immunohistochemistry: suitable | |
| immunoprecipitation (IP): suitable | |
| indirect ELISA: suitable | |
| western blot: 1:2,000 | |
| UniProt accession no. | Q9Y5R2  |
| Biochem/physiol Actions: | Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer. |
| Biochem/physiol Actions: | Reacts with reduced and native MMP-24. Recognizes the pro-form of MMP-24 as well as activation/breakdown products. |
| General description: | Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20. |
| Immunogen: | synthetic peptide corresponding to the hinge region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5). |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |