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Myricetin

SIGMA/M6760 - ≥96.0%, crystalline

Synonym: 3,3′,4′,5,5′,7-Hexahydroxyflavone; Cannabiscetin; Myricetol

CAS Number: 529-44-2
Empirical Formula (Hill Notation): C15H10O8
Molecular Weight: 318.24
EC Number: 208-463-2
MDL Number: MFCD00006827
Linear Formula: C15H10O8
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-M6760-10MG 10 mg
$85.70
1/EA
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45-M6760-25MG 25 mg
$171.00
1/EA
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assay ≥96.0%
form crystalline
InChI 1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
InChI key IKMDFBPHZNJCSN-UHFFFAOYSA-N
mp >300 °C (lit.)
Quality Level 100 
SMILES string Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3
solubility absolute ethanol: 10 mg/mL, clear to slightly hazy, yellow to very deep greenish-yellow
Application: Myricetin has been used:
• to investigate its effect on end product (AGE)- bovine serum albumin mediated phosphorylation of mitogen-activated protein kinase(ERK1)
• as a standard for the quantification of phenolics from noni plant extracts using high performance liquid chromatography(HPLC)
• as a standard for characterization of phenolic compounds from Hibiscus sabdariffa using ultra-high performance liquid chromatography(UHPLC)

Biochem/physiol Actions: Myricetin is a naturally occurring flavonol with antioxidant property. It displays moderate membrane permeability and it degrades rapidly at elevated pH. Myricetin is one of the major flavonoid present in edible plants and has anticarcinogenic and antimutagenic functionality. It comprises of two benzene rings A and B. Ring B intercalates with nucleotide staking and inhibits bacterial DNA synthesis. Myricetin elicits protective function against oxidative stress generated by tert-butylhydroperoxide (t-BHP) in diabetic rat and improves glutathione peroxidase (GPx) and xanthine oxidase (XO) enzyme activity. It also lowers the glycation of low-density lipoprotein.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥96.0%
mp >300 °C (lit.)
UNSPSC 12352202

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