gamma-Mangostin
SIGMA/M6824 - ≥98% (HPLC)
Synonym: 1,3,6,7-
CAS Number: 31271-07-5
Empirical Formula (Hill Notation): C23H24O6
Molecular Weight: 396.43
MDL Number: MFCD00951752
Linear Formula: C23H24O6
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M6824-10MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: M6824-50MG
This image depicts SKU: M6824-50MG
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| color | off-white to yellow |
| form | powder |
| InChI | 1S/C23H24O6/c1-11(2)5-7-1 |
| InChI key | VEZXFTKZUMARDU-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | OC1=CC(OC2=CC(O)=C(CC=C(C |
| solubility | methanol: 1 mg/mL, colorless to yellow |
| storage temp. | 2-8°C |
| Application: | γ-Mangostin has been used to study its inhibitory effect on Transthyretin (TTR) fibrillization, a homotetrameric protein involved in human hereditary amyloidosis. |
| Biochem/physiol Actions: | The xanthone derivatives, namely α-, β-, and γ-mangostin have various biological activities including antiproliferative and anti-inflammatory activity, enhancement of natural killer (NK) cell activity, and antiviral effect against human immunodeficiency virus (HIV). γ-Mangostin is also reported to inhibit cyclooxygenase (COX-2) activity and NO production, which in turn reduces the level of prostaglandin E2. It is found to induce cell death in human colon cancer cells. |
| Biochem/physiol Actions: | Xanthone derivative isolated from the mangosteen hull (Garcinia mangostana). Exhibits antioxidant and anticancer properties. Mangosteen xanthones inhibit inflammation in human adipocytes which is important in understanding obesity-associated inflammation and the development of insulin resistance. |
| General description: | The fruit hulls of mangosteen contain three major bioactive compounds namely, α-, β-, and γ-mangostin. |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 50 mg in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |