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NG-Methyl-L-arginine acetate salt

SIGMA/M7033 - ≥98% (TLC)

Synonym: Nω-Methyl-L-arginine acetate salt; L-NMMA; N5-(Methylamidino)-L-ornithine acetate salt; NG-Monomethyl-L-arginine acetate salt

CAS Number: 53308-83-1
Empirical Formula (Hill Notation): C7H16N4O2 · C2H4O2
Molecular Weight: 248.28
MDL Number: MFCD00069311
Linear Formula: C7H16N4O2 · C2H4O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M7033-5MG 5 mg
 $50.20
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45-M7033-25MG 25 mg
 $156.00
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45-M7033-100MG 100 mg
 $467.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7033-25MG

 

assay ≥98% (TLC)
form powder
InChI 1S/C7H16N4O2.C2H4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13;1-2(3)4/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H3,(H,3,4)/t5-;/m0./s1
InChI key IKPNWIGTWUZCKM-JEDNCBNOSA-N
Quality Level 200 
SMILES string CC(O)=O.CNC(=N)NCCC[C@H](N)C(O)=O
solubility water: 49.00-51.00 mg/mL, clear to very slightly hazy, colorless to faintly yellow
Application: NG-Methyl-L-arginine acetate salt has been used:
• as an inhibitor of nitric oxide synthase (NOS) in wound healing studies in injured mice
• as an inhibitor of nitric oxide synthase (NOS) to study nitric oxide (NO) immunosuppressive effect of murine stem cells
• as an inhibitor to monitor NO levels in hemocytes respiratory burst assay
Biochem/physiol Actions: NG-Methyl-L-arginine is an inhibitor of nitric oxide synthase in neurons, endothelial cells, and macrophages. It inhibits endothelium-derived relaxing factor and promotes contraction in pulmonary artery and vein. It stereo selectively inhibits the generation of nitric oxide (NO) from arginine. It promotes epinephrine and glucose levels, contributing to hyperglycemia in central nervous system.
Features and Benefits: This compound is featured on the Nitric Oxide Synthases  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
UNSPSC 12352209

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