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4-Methylumbelliferyl sulfate potassium salt

SIGMA/M7133 - sulfatase substrate

Synonym: Potassium 4-methylumbelliferyl sulfate

CAS Number: 15220-11-8
Empirical Formula (Hill Notation): C10H7KO6S
Molecular Weight: 294.32
EC Number: 239-272-2
MDL Number: MFCD00016970
Linear Formula: C10H7KO6S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M7133-500MG 500 mg
 $214.00
1/EA		 Add To Favorites
45-M7133-1G 1 g
 $393.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7133-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7133-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7133-500MG

 

assay ≥99% (HPLC)
fluorescence λex 334 nm; λem 370 nm (pH 10.4)
  λex 360 nm; λem 449 nm (Reaction products)
form powder
InChI 1S/C10H8O6S.K/c1-6-4-10(11)15-9-5-7(2-3-8(6)9)16-17(12,13)14;/h2-5H,1H3,(H,12,13,14);/q;+1/p-1
InChI key CSOCSPXOODWGLJ-UHFFFAOYSA-M
Quality Level 200 
SMILES string [K+].CC1=CC(=O)Oc2cc(OS([O-])(=O)=O)ccc12
solubility water: 5 mg/mL, clear, colorless
storage temp. −20°C
Application: 4-Methylumbelliferyl sulfate potassium salt has been used as a substrate in coupled fluorescence sulfotransferase assay to regenerate 3′-phosphoadenosine 5′-phosphosulfate (PAPS) from 3′-phosphoadenosine 5′-phosphate for cerebroside sulfotransferase (CST) enzyme activity measurements. It has also been used as a substrate in arylsulfatase assay/4-methylumbelliferyl sulfate (4-MUS) assay to test the enzymatic activity of the protein-bead complex.
Biochem/physiol Actions: 4-Methylumbelliferyl sulfate (4MUS) is capable of undergoing desulfation and involve in futile cycling with 4MU. It can be utilized to measure the arylsulfatase activity of several sulfatases.
General description: 4-Methylumbelliferyl sulfate (4MUS), a general substrate, is a polar metabolite of 4-methylumbelliferone (4MU).
Packaging: 1 g in poly bottle
Packaging: 500 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99% (HPLC)
Storage Temp. −20°C
UNSPSC 12352204

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