L-(−)-Malic acid
SIGMA/M7397 - suitable for cell culture, BioReagent, suitable for insect cell culture
Synonym: (S)-(−)-2-Hydroxysuccinic acid; L-Hydroxybutanedioic acid
CAS Number: 97-67-6
Empirical Formula (Hill Notation): C4H6O5
Molecular Weight: 134.09
EC Number: 202-601-5
MDL Number: MFCD00064213
Linear Formula: HO2CCH2CH(OH)CO2H
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7397-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7397-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M7397-25G
| assay | ≥95% (titration) |
| biological source | microbial |
| form | powder |
| InChI | 1S/C4H6O5/c5-2(4(8)9)1-3( |
| InChI key | BJEPYKJPYRNKOW-REOHCLBHSA |
| mp | 101-103 °C (lit.) |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | O[C@@H](CC(O)=O)C(O)=O |
| solubility | water: 100 mg/mL, clear to slightly hazy, colorless |
| technique(s) | cell culture | insect: suitable |
| cell culture | mammalian: suitable |
| Application: | Malic acid has been used: • to induce basal respiration in mitochondrial cell culture • to measure the mitochondrial ETC (electron transport chain) activity • as a component of mitochondrial substrate stock |
| Biochem/physiol Actions: | Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle. |
| General description: | Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices. |
| Packaging: | 25, 100, 500 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥95% (titration) |
| mp | 101-103 °C (lit.) |
| UNSPSC | 12352205 |