IgG2a, Kappa from murine myeloma
SIGMA/M7769 - clone UPC 10, ascites fluid, lyophilized powder
Synonym: Mouse IgG2a-κ
MDL Number: MFCD00164800
Product Type: Chemical
Illustration of IgG2a, Kappa.
| antibody form | ascites fluid |
| biological source | mouse |
| clone | UPC 10, monoclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 300  |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Application: | IgG2a, Kappa from murine myeloma has been used in immunofluorescence and immunohistochemistry. |
| Biochem/physiol Actions: | Antigen Specificity: β-2,6-fructosan Trace amounts of lambda chain may be present. |
| Biochem/physiol Actions: | The IgG2a (immunoglobulin G 2a) plays a vital role in stimulating autoimmunity in mice. This gene is expressed at high level during virus infection. IgG2a offers host defence through activation of complement system. This antibody has specificity towards Fc receptors expressed on phagocytes and stimulates antibody-dependent cell mediated cytotoxicity. IgG2a also induces macrophage-mediated opsonophagocytosis, which has been observed in response to influenza virus and leads to its clearance from the infected cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | The UPC-10 tumor line that produces mouse IgG2a, |
| Immunogen: | The UPC-10 tumor line that produces mouse IgG2a, |
| Physical form: | The product provided is lyophilized from 0.01 M phosphate buffered saline, pH 7.2, with no preservatives added. |
| Preparation Note: | Storage and Stability: Store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |