Monoclonal Anti-Thy 1.1 antibody produced in mouse
SIGMA/M7898 - clone TN-26, purified immunoglobulin, buffered aqueous solution
Synonym: Anti-CD90; Anti-CDw90
MDL Number: MFCD00164701
Product Type: Chemical
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| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | TN-26, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgM |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | complement-mediated cytotoxicity assay: suitable |
| indirect immunofluorescence: suitable | |
| UniProt accession no. | P01831  |
| Application: | Monoclonal Anti-Thy 1.1 antibody produced in mouse has been used in immunopanning and immunofluorescence. |
| Biochem/physiol Actions: | Recognizes Thy 1.1 bearing cells and is less than 5% cross-reactive with Thy 1.2 bearing cells. Titer is 1:20,000 as determined by in vitro cytotoxicity against AKR/J thymocytes. |
| Biochem/physiol Actions: | Studies have shown that mice lacking the protein thymus cell antigen 1 (Thy 1.1) have an increased number of fibroblasts. It suppresses proliferation and enhances apoptosis in dermal fibroblasts, thereby modulating cell growth. This is carried out by regulating the action of β3 integrin. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Monoclonal Anti-Thy 1.1 (mouse IgM isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. |
| General description: | Thymus cell antigen 1 (Thy 1.1) is a glycosylphosphatidyl-anch |
| Immunogen: | thymocytes from AKR/J (Thy 1.1) mice. |
| Physical form: | Solution in 0.1 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| Hazard Codes | Xn |
| Risk Statements | 21/22 |
| Safety Statements | 36/37-60 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |