Mephetyl tetrazole

SIGMA/M7945 - ≥98% (HPLC), oil

Synonym: 1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole

CAS Number: 916923-10-9
Empirical Formula (Hill Notation): C₂₀H₂₂N₄O
Molecular Weight: 334.41
MDL Number: MFCD11045297
Linear Formula: C₂₀H₂₂N₄O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-M7945-5MG	5 mg	$219.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	pale yellow
form	oil
InChI	1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3
InChI key	VREPWWBWXVLSEF-UHFFFAOYSA-N
Quality Level	100
SMILES string	COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1
solubility	DMSO: >5 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	Mephetyl tetrazole is a potent and selective K_v1.5 potassium channel blocker.
Biochem/physiol Actions:	Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC₅₀ = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.
Features and Benefits:	This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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