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MAN-5 Glycan

SIGMA/M8449 - ≥90% (HPLC)

Synonym: (Man)5(GlcNAc)2; Mannopentaose-di-(N-acetyl-D-glucosamine); Oligomannose-5 glycan

CAS Number: 66091-47-2
Empirical Formula (Hill Notation): C46H78N2O36
Molecular Weight: 1235.10
MDL Number: MFCD00467030
Linear Formula: C46H78N2O36
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M8449-10UG 10 µg
 $385.00
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assay ≥90% (HPLC)
form solid
InChI 1S/C46H78N2O36/c1-11(55)47-13(3-49)22(58)37(14(57)4-50)81-41-21(48-12(2)56)28(64)38(18(8-54)78-41)82-46-36(72)40(84-45-34(70)31(67)25(61)17(7-53)77-45)27(63)20(80-46)10-74-43-35(71)39(83-44-33(69)30(66)24(60)16(6-52)76-44)26(62)19(79-43)9-73-42-32(68)29(65)23(59)15(5-51)75-42/h3,13-46,50-54,57-72H,4-10H2,1-2H3,(H,47,55)(H,48,56)
InChI key KIAGZJJOMMNKBW-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC(=O)NC(C=O)C(O)C(OC1OC(CO)C(OC2OC(COC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(OC5OC(CO)C(O)C(O)C5O)C3O)C(O)C(OC6OC(CO)C(O)C(O)C6O)C2O)C(O)C1NC(C)=O)C(O)CO
storage temp. −20°C
Biochem/physiol Actions: Antibodies bearing high levels of N-linked mannose-5 glycan (Man-5) have been found to exhibit enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) when compared to antibodies with fucosylated complex or hybrid glycans.
Biochem/physiol Actions: Antibodies carrying high levels of N-linked mannose-5 glycan (Man5) possesses increased antibody-dependent cell-mediated cytotoxicity (ADCC) than antibodies with fucosylated complex or hybrid glycans.
Other Notes: To gain a comprehensive understanding of our extensive range of Oligosaccharides  for your research, we encourage you to visit our Carbohydrates  Category page.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥90% (HPLC)
Storage Temp. −20°C
UNSPSC 12352201

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